Alternative polyadenylation: methods, mechanism, function, and role in cancer
Alternative polyadenylation: methods, mechanism, function, and role in cancer
About this item
Full title
Author / Creator
Zhang, Yi , Liu, Lian , Qiu, Qiongzi , Zhou, Qing , Ding, Jinwang , Lu, Yan and Liu, Pengyuan
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Occurring in over 60% of human genes, alternative polyadenylation (APA) results in numerous transcripts with differing 3'ends, thus greatly expanding the diversity of mRNAs and of proteins derived from a single gene. As a key molecular mechanism, APA is involved in various gene regulation steps including mRNA maturation, mRNA stability, cellular RN...
Alternative Titles
Full title
Alternative polyadenylation: methods, mechanism, function, and role in cancer
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ee8c544323ef42cd88220946fc193428
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee8c544323ef42cd88220946fc193428
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-021-01852-7
