Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors
Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Complex carbohydrates (glycans) are major players in all organisms due to their structural, energy, and communication roles. This last essential role involves interacting and/or signaling through a plethora of glycan-binding proteins. The design and synthesis of glycans as potential drug candidates that selectively alter or perturb metabolic proces...
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Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_ef461400591343048c9e59e0041eaaf1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef461400591343048c9e59e0041eaaf1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-34788-3
