UFL1 promotes histone H4 ufmylation and ATM activation
UFL1 promotes histone H4 ufmylation and ATM activation
About this item
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Author / Creator
Qin, Bo , Yu, Jia , Nowsheen, Somaira , Wang, Minghui , Tu, Xinyi , Liu, Tongzheng , Li, Honglin , Wang, Liewei and Lou, Zhenkun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The ataxia-telangiectasia mutated (ATM) kinase, an upstream kinase of the DNA damage response (DDR), is rapidly activated following DNA damage, and phosphorylates its downstream targets to launch DDR signaling. However, the mechanism of ATM activation is still not completely understood. Here we report that UFM1 specific ligase 1 (UFL1), an ufmylati...
Alternative Titles
Full title
UFL1 promotes histone H4 ufmylation and ATM activation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ef61338d640d4b1f97d227ca1abf24ce
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef61338d640d4b1f97d227ca1abf24ce
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09175-0
