Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2
Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Matrix metalloproteinases (MMPs) are regulated at multiple transcriptional and post-transcriptional levels, among which receptor-mediated endocytic clearance. We previously showed that low-density lipoprotein receptor-related protein-1 (LRP-1) mediates the clearance of a complex between the zymogen form of MMP-2 (proMMP-2) and tissue inhibitor of m...
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Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2
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TN_cdi_doaj_primary_oai_doaj_org_article_ef8ab5cbd1544d42a3b9b4dc04fabb65
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef8ab5cbd1544d42a3b9b4dc04fabb65
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-04648-y
