SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal bre...
SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Cancer cells exhibit altered metabolism, often relying on glutamine (Gln) for growth. Breast cancer (BC) is a heterogeneous disease with varying clinical outcomes. We investigated the role of the amino acid transporter SLC1A5 (ASCT2) and its association with BC subtypes and patient outcomes. In large BC cohorts,
SLC1A5
mRNA (n = 9488) and SLC...
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Full title
SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_ef9463513fea44e0adae2d14a5af1821
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef9463513fea44e0adae2d14a5af1821
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-87292-1
