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Development of a first-in-class antibody and a specific assay for α-1,6-fucosylated prostate-specifi...

Development of a first-in-class antibody and a specific assay for α-1,6-fucosylated prostate-specifi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef98887a925b43faa0aac0379ac42831

Development of a first-in-class antibody and a specific assay for α-1,6-fucosylated prostate-specific antigen

About this item

Full title

Development of a first-in-class antibody and a specific assay for α-1,6-fucosylated prostate-specific antigen

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-07, Vol.14 (1), p.16512-11, Article 16512

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Prostate-specific antigen (PSA) levels are widely used to screen for prostate cancer, yet the test has poor sensitivity, specificity and predictive value, which leads to overdiagnosis and overtreatment. Alterations in the glycosylation status of PSA, including fucosylation, may offer scope for an improved biomarker. We sought to generate a monoclon...

Alternative Titles

Full title

Development of a first-in-class antibody and a specific assay for α-1,6-fucosylated prostate-specific antigen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ef98887a925b43faa0aac0379ac42831

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef98887a925b43faa0aac0379ac42831

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-67545-1

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