Development of a first-in-class antibody and a specific assay for α-1,6-fucosylated prostate-specifi...
Development of a first-in-class antibody and a specific assay for α-1,6-fucosylated prostate-specific antigen
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Prostate-specific antigen (PSA) levels are widely used to screen for prostate cancer, yet the test has poor sensitivity, specificity and predictive value, which leads to overdiagnosis and overtreatment. Alterations in the glycosylation status of PSA, including fucosylation, may offer scope for an improved biomarker. We sought to generate a monoclon...
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Development of a first-in-class antibody and a specific assay for α-1,6-fucosylated prostate-specific antigen
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TN_cdi_doaj_primary_oai_doaj_org_article_ef98887a925b43faa0aac0379ac42831
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ef98887a925b43faa0aac0379ac42831
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-67545-1