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ALKBH5 promotes PD-L1-mediated immune escape through m6A modification of ZDHHC3 in glioma

ALKBH5 promotes PD-L1-mediated immune escape through m6A modification of ZDHHC3 in glioma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_efcc1ba016cd4a049b862a25d1a80150

ALKBH5 promotes PD-L1-mediated immune escape through m6A modification of ZDHHC3 in glioma

About this item

Full title

ALKBH5 promotes PD-L1-mediated immune escape through m6A modification of ZDHHC3 in glioma

Publisher

London: Nature Publishing Group UK

Journal title

Cell death discovery, 2022-12, Vol.8 (1), p.497-497, Article 497

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

N6-methylation of adenosine (m6A) is one of the most frequent chemical modifications in eukaryotic RNAs and plays a vital role in tumorigenesis and progression. Recently, emerging studies have shown that m6A modification by ALKBH5 was associated with immunotherapy response in various types of cancer. However, whether m6A demethylases ALKBH5 partici...

Alternative Titles

Full title

ALKBH5 promotes PD-L1-mediated immune escape through m6A modification of ZDHHC3 in glioma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_efcc1ba016cd4a049b862a25d1a80150

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_efcc1ba016cd4a049b862a25d1a80150

Other Identifiers

ISSN

2058-7716

E-ISSN

2058-7716

DOI

10.1038/s41420-022-01286-w

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