Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macroph...
Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages
About this item
Full title
Author / Creator
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Sciences Publications Ltd
Subjects
More information
Scope and Contents
Contents
Bisphosphonates drugs target the skeleton and are used globally for the treatment of common bone disorders. Nitrogen-containing bisphosphonates act by inhibiting the mevalonate pathway in bone-resorbing osteoclasts but, surprisingly, also appear to reduce the risk of death from pneumonia. We overturn the long-held belief that these drugs act only i...
Alternative Titles
Full title
Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_efd2366c282f45e0a4b6b5d87db2968d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_efd2366c282f45e0a4b6b5d87db2968d
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.72430
