The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes
The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes
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England: eLife Science Publications, Ltd
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Language
English
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England: eLife Science Publications, Ltd
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Altered Ca
handling is often present in diseased hearts undergoing structural remodeling and functional deterioration. However, whether Ca
directly regulates sarcomere structure has remained elusive. Using a zebrafish
mutant, we explored the impacts of impaired Ca
homeostasis on myofibril integrity. We found that the E3 ubiquitin ligase...
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Full title
The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes
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TN_cdi_doaj_primary_oai_doaj_org_article_efe360faa79f481eb6f76f71d47df7de
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_efe360faa79f481eb6f76f71d47df7de
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.27955
