Iron overload inhibits self‐renewal of human pluripotent stem cells via DNA damage and generation of...
Iron overload inhibits self‐renewal of human pluripotent stem cells via DNA damage and generation of reactive oxygen species
About this item
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Author / Creator
Han, Zhenbo , Xu, Zihang , Chen, Lei , Ye, Danyu , Yu, Yang , Zhang, Ying , Cao, Yang , Djibril, Bamba , Guo, Xiaofei , Gao, Xinlu , Zhang, Wenwen , Yu, Meixi , Liu, Shenzhen , Yan, Gege , Jin, Mengyu , Huang, Qi , Wang, Xiuxiu , Hua, Bingjie , Feng, Chao , Yang, Fan , Ma, Wenya and Liu, Yu
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Iron overload affects the cell cycle of various cell types, but the effect of iron overload on human pluripotent stem cells has not yet been reported. Here, we show that the proliferation capacities of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) were significantly inhibited by ferric ammonium citrate (FAC) i...
Alternative Titles
Full title
Iron overload inhibits self‐renewal of human pluripotent stem cells via DNA damage and generation of reactive oxygen species
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f008a508145c41ed97901068f7ea32c3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f008a508145c41ed97901068f7ea32c3
Other Identifiers
ISSN
2211-5463
E-ISSN
2211-5463
DOI
10.1002/2211-5463.12811
