Modular actin nano-architecture enables podosome protrusion and mechanosensing
Modular actin nano-architecture enables podosome protrusion and mechanosensing
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Author / Creator
van den Dries, Koen , Nahidiazar, Leila , Slotman, Johan A. , Meddens, Marjolein B. M. , Pandzic, Elvis , Joosten, Ben , Ansems, Marleen , Schouwstra, Joost , Meijer, Anke , Steen, Raymond , Wijers, Mietske , Fransen, Jack , Houtsmuller, Adriaan B. , Wiseman, Paul W. , Jalink, Kees and Cambi, Alessandra
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Basement membrane transmigration during embryonal development, tissue homeostasis and tumor invasion relies on invadosomes, a collective term for invadopodia and podosomes. An adequate structural framework for this process is still missing. Here, we reveal the modular actin nano-architecture that enables podosome protrusion and mechanosensing. The...
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Full title
Modular actin nano-architecture enables podosome protrusion and mechanosensing
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f02ec8baa69243f385139e1d26c11672
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f02ec8baa69243f385139e1d26c11672
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13123-3
