Virtual Screening for Potential Phytobioactives as Therapeutic Leads to Inhibit NQO1 for Selective A...
Virtual Screening for Potential Phytobioactives as Therapeutic Leads to Inhibit NQO1 for Selective Anticancer Therapy
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Author / Creator
Shreevatsa, Bhargav , Dharmashekara, Chandan , Swamy, Vikas Halasumane , Gowda, Meghana V. , Achar, Raghu Ram , Kameshwar, Vivek Hamse , Thimmulappa, Rajesh Kumar , Syed, Asad , Elgorban, Abdallah M. , Al-Rejaie, Salim S. , Ortega-Castro, Joaquín , Frau, Juan , Flores-Holguín, Norma , Shivamallu, Chandan , Kollur, Shiva Prasad and Glossman-Mitnik, Daniel
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
NAD(P)H:quinone acceptor oxidoreductase-1 (NQO1) is a ubiquitous flavin adenine dinucleotide-dependent flavoprotein that promotes obligatory two-electron reductions of quinones, quinonimines, nitroaromatics, and azo dyes. NQO1 is a multifunctional antioxidant enzyme whose expression and deletion are linked to reduced and increased oxidative stress...
Alternative Titles
Full title
Virtual Screening for Potential Phytobioactives as Therapeutic Leads to Inhibit NQO1 for Selective Anticancer Therapy
Authors, Artists and Contributors
Author / Creator
Dharmashekara, Chandan
Swamy, Vikas Halasumane
Gowda, Meghana V.
Achar, Raghu Ram
Kameshwar, Vivek Hamse
Thimmulappa, Rajesh Kumar
Syed, Asad
Elgorban, Abdallah M.
Al-Rejaie, Salim S.
Ortega-Castro, Joaquín
Frau, Juan
Flores-Holguín, Norma
Shivamallu, Chandan
Kollur, Shiva Prasad
Glossman-Mitnik, Daniel
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f039d1eae82d4a3b8bc5c8c39db5e75f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f039d1eae82d4a3b8bc5c8c39db5e75f
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules26226863