The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DN...
The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Prolonged cell survival occurs through the expression of specific protein isoforms generated by alternate splicing of mRNA precursors in cancer cells. How alternate splicing regulates tumor development and resistance to targeted therapies in cancer remain poorly understood. Here we show that RNF113A, whose loss-of-function causes the X-linked trich...
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Full title
The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
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TN_cdi_doaj_primary_oai_doaj_org_article_f0459d053d834898b297f47efd32aaed
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f0459d053d834898b297f47efd32aaed
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15003-7
