Sexual dimorphism in glucose metabolism is shaped by androgen-driven gut microbiome
Sexual dimorphism in glucose metabolism is shaped by androgen-driven gut microbiome
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Author / Creator
Gao, Aibo , Su, Junlei , Liu, Ruixin , Zhao, Shaoqian , Li, Wen , Xu, Xiaoqiang , Li, Danjie , Shi, Juan , Gu, Bin , Zhang, Juan , Li, Qi , Wang, Xiaolin , Zhang, Yifei , Xu, Yu , Lu, Jieli , Ning, Guang , Hong, Jie , Bi, Yufang , Gu, Weiqiong , Wang, Jiqiu and Wang, Weiqing
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Males are generally more susceptible to impaired glucose metabolism and type 2 diabetes (T2D) than females. However, the underlying mechanisms remain to be determined. Here, we revealed that gut microbiome depletion abolished sexual dimorphism in glucose metabolism. The transfer of male donor microbiota into antibiotics-treated female mice led the...
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Full title
Sexual dimorphism in glucose metabolism is shaped by androgen-driven gut microbiome
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TN_cdi_doaj_primary_oai_doaj_org_article_f0610e4af26d42ca95565a83bdcbe89f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f0610e4af26d42ca95565a83bdcbe89f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27187-7