Evaluation of a multiphasic parasite clearance profile after treatment of experimental human infecti...
Evaluation of a multiphasic parasite clearance profile after treatment of experimental human infection with the investigational anti-malarial M5717 using segmented mixed effect models
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Evaluation of parasite clearance patterns in experimental human infection trials helps increase understanding of drug action. In a previously reported phase Ib trial of a new investigational anti-malarial drug M5717, parasite clearance showed a biphasic linear pattern: slow removal phase with a near flat clearance rate followed by a fast clearance...
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Full title
Evaluation of a multiphasic parasite clearance profile after treatment of experimental human infection with the investigational anti-malarial M5717 using segmented mixed effect models
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TN_cdi_doaj_primary_oai_doaj_org_article_f06f350695e94c21af64078bdc6defd9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f06f350695e94c21af64078bdc6defd9
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ISSN
1475-2875
E-ISSN
1475-2875
DOI
10.1186/s12936-023-04627-x
