Loss of SMYD1 Results in Perinatal Lethality via Selective Defects within Myotonic Muscle Descendant...
Loss of SMYD1 Results in Perinatal Lethality via Selective Defects within Myotonic Muscle Descendants
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
SET and MYND Domain 1 (SMYD1) is a cardiac and skeletal muscle-specific, histone methyl transferase that is critical for both embryonic and adult heart development and function in both mice and men. We report here that skeletal muscle-specific,
-mediated conditional knockout (CKO) of
results in perinatal death. As early as embryonic day 12.5,...
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Full title
Loss of SMYD1 Results in Perinatal Lethality via Selective Defects within Myotonic Muscle Descendants
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TN_cdi_doaj_primary_oai_doaj_org_article_f083663d1bfd4692be46b5f1c4801cac
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f083663d1bfd4692be46b5f1c4801cac
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ISSN
2079-9721
E-ISSN
2079-9721
DOI
10.3390/diseases7010001
