Age-related accumulation of T cells with markers of relatively stronger autoreactivity leads to func...
Age-related accumulation of T cells with markers of relatively stronger autoreactivity leads to functional erosion of T cells
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Thymic involution is a prominent characteristic of an aging immune system. When thymic function is reduced/absent, the peripheral T cell pool is subject to the laws of peripheral T cell homeostasis that favor survival/expansion of T cell receptors with relatively higher functional avidity for self-peptide/MHC complexes. Due to difficulties in asses...
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Full title
Age-related accumulation of T cells with markers of relatively stronger autoreactivity leads to functional erosion of T cells
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TN_cdi_doaj_primary_oai_doaj_org_article_f09e54045c834fd988b10c8d9f7cad25
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f09e54045c834fd988b10c8d9f7cad25
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ISSN
1471-2172
E-ISSN
1471-2172
DOI
10.1186/1471-2172-13-8
