Bevacizumab treatment for radiation brain necrosis: mechanism, efficacy and issues
Bevacizumab treatment for radiation brain necrosis: mechanism, efficacy and issues
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Vascular damage is followed by vascular endothelial growth factor (VEGF) expression at high levels, which is an important mechanism forradiation brain necrosis development. Bevacizumab alleviates brain edema symptoms caused by radiation brain necrosis through inhibiting VEGF and acting on vascular tissue around the brain necrosis area. Many studies...
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Full title
Bevacizumab treatment for radiation brain necrosis: mechanism, efficacy and issues
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TN_cdi_doaj_primary_oai_doaj_org_article_f0afa385d0a84a5b98dc0a9f9a75ed39
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f0afa385d0a84a5b98dc0a9f9a75ed39
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-019-0950-1
