Recombinant Adenovirus KGHV500 and CIK Cells Codeliver Anti-p21-Ras scFv for the Treatment of Gastri...
Recombinant Adenovirus KGHV500 and CIK Cells Codeliver Anti-p21-Ras scFv for the Treatment of Gastric Cancer with Wild-Type Ras Overexpression
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Author / Creator
Wang, Mingjuan , Hong, Yanling , Feng, Qiang , Pan, Xinyan , Song, Shuling , Cui, Jing , Lei, Jin , Fang, Hong and Yang, Julun
Publisher
United States: Elsevier Inc
Journal title
Language
English
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Publication information
Publisher
United States: Elsevier Inc
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More information
Scope and Contents
Contents
The development of gastric cancer is frequently related to the overexpression of wild-type p21 proteins, but it is rarely related to mutated Ras proteins. We previously constructed a broad-spectrum anti-p21-Ras single-chain variable fragment antibody (scFv), which was carried by the oncolytic adenovirus KGHV500. Here we explored the antitumor effec...
Alternative Titles
Full title
Recombinant Adenovirus KGHV500 and CIK Cells Codeliver Anti-p21-Ras scFv for the Treatment of Gastric Cancer with Wild-Type Ras Overexpression
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f0c6d49ffb034905b8cc8190060c7481
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f0c6d49ffb034905b8cc8190060c7481
Other Identifiers
ISSN
2372-7705
E-ISSN
2372-7705
DOI
10.1016/j.omto.2018.10.003
