Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of...
Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Microglia-mediated neuroinflammation has been implicated in the pathogenesis of Alzheimer’s disease (AD). Although microglia in aging and neurodegenerative disease model mice show a loss of homeostatic phenotype and activation of disease-associated microglia (DAM), a correlation between those phenotypes and the degree of neuronal cell loss has not...
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Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_f0f701e9e83d46abbb0f133d94d230a5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f0f701e9e83d46abbb0f133d94d230a5
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-020-01099-x
