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E proteins control the development of NKγδT cells through their invariant T cell receptor

E proteins control the development of NKγδT cells through their invariant T cell receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f10d24a302ee49119e6cd90778ad9580

E proteins control the development of NKγδT cells through their invariant T cell receptor

About this item

Full title

E proteins control the development of NKγδT cells through their invariant T cell receptor

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-06, Vol.15 (1), p.5078-14, Article 5078

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

T cell receptor (TCR) signaling regulates important developmental transitions, partly through induction of the E protein antagonist, Id3. Although normal γδ T cell development depends on Id3, Id3 deficiency produces different phenotypes in distinct γδ T cell subsets. Here, we show that Id3 deficiency impairs development of the Vγ3
+
subset, w...

Alternative Titles

Full title

E proteins control the development of NKγδT cells through their invariant T cell receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f10d24a302ee49119e6cd90778ad9580

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f10d24a302ee49119e6cd90778ad9580

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-49496-3

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