Structure-Based Design of Potent and Selective Ligands at the Four Adenosine Receptors
Structure-Based Design of Potent and Selective Ligands at the Four Adenosine Receptors
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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The four receptors that signal for adenosine, A1, A2A, A2B and A3 ARs, belong to the superfamily of G protein-coupled receptors (GPCRs). They mediate a number of (patho)physiological functions and have attracted the interest of the biopharmaceutical sector for decades as potential drug targets. The many crystal structures of the A2A, and lately the...
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Structure-Based Design of Potent and Selective Ligands at the Four Adenosine Receptors
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TN_cdi_doaj_primary_oai_doaj_org_article_f115c7958c5a494a9a1eab7fe8bc2ac6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f115c7958c5a494a9a1eab7fe8bc2ac6
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ISSN
1420-3049,1431-5157
E-ISSN
1420-3049
DOI
10.3390/molecules22111945
