PCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chr...
PCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chromatin interactions
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Author / Creator
Huang, Xiaona , Wei, Chao , Li, Fenjie , Jia, Lumeng , Zeng, Pengguihang , Li, Jiahe , Tan, Jin , Sun, Tuanfeng , Jiang, Shaoshuai , Wang, Jia , Tang, Xiuxiao , Zhao, Qingquan , Liu, Bin , Rong, Limin , Li, Cheng and Ding, Junjun
Publisher
Beijing: Higher Education Press
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Language
English
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Publisher
Beijing: Higher Education Press
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Contents
Polycomb group (PcG) ring finger protein 6 (PCGF6), though known as a member of the transcription-repressing complexes, PcG, also has activation function in regulating pluripotency gene expression. However, the mechanism underlying the activation function of PCGF6 is poorly understood. Here, we found that PCGF6 co-localizes to gene activation regio...
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Full title
PCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chromatin interactions
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TN_cdi_doaj_primary_oai_doaj_org_article_f1662bece80242d6a6e8ffd5d9627afa
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f1662bece80242d6a6e8ffd5d9627afa
Other Identifiers
ISSN
1674-800X
E-ISSN
1674-8018
DOI
10.1007/s13238-019-0629-9