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The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic...

The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f16d777b16254fa69d0b0a1b290402cf

The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch

About this item

Full title

The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2019-01, Vol.12 (1)

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

The development of the aortic arch is a complex process that involves remodeling of the bilaterally symmetrical pharyngeal arch arteries (PAAs) into the mature asymmetric aortic arch. Retinoic acid signaling is a key regulator of this process by directing patterning of the second heart field (SHF), formation of the caudal PAAs and subsequent remode...

Alternative Titles

Full title

The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f16d777b16254fa69d0b0a1b290402cf

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f16d777b16254fa69d0b0a1b290402cf

Other Identifiers

ISSN

1754-8403

E-ISSN

1754-8411

DOI

10.1242/dmm.036491

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