Epigenetic regulator UHRF1 orchestrates proinflammatory gene expression in rheumatoid arthritis in a...
Epigenetic regulator UHRF1 orchestrates proinflammatory gene expression in rheumatoid arthritis in a suppressive manner
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United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Rheumatoid arthritis (RA) is characterized by chronic synovial inflammation with aberrant epigenetic alterations, eventually leading to joint destruction. However, the epigenetic regulatory mechanisms underlying RA pathogenesis remain largely unknown. Here, we showed that ubiquitin-like containing PHD and RING finger domains 1 (UHRF1) is a central...
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Full title
Epigenetic regulator UHRF1 orchestrates proinflammatory gene expression in rheumatoid arthritis in a suppressive manner
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TN_cdi_doaj_primary_oai_doaj_org_article_f1838a9b286847508d31911b8c6d40b6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f1838a9b286847508d31911b8c6d40b6
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI150533
