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Cardiac pericytes mediate the remodeling response to myocardial infarction

Cardiac pericytes mediate the remodeling response to myocardial infarction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f18ebf825bbb4dbca6e73911d2a8ceaf

Cardiac pericytes mediate the remodeling response to myocardial infarction

About this item

Full title

Cardiac pericytes mediate the remodeling response to myocardial infarction

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2023-05, Vol.133 (10), p.1-16

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Despite the prevalence of pericytes in the microvasculature of the heart, their role during ischemia-induced remodeling remains unclear. We used multiple lineage-tracing mouse models and found that pericytes migrated to the injury site and expressed profibrotic genes, coinciding with increased vessel leakage after myocardial infarction (MI). Single...

Alternative Titles

Full title

Cardiac pericytes mediate the remodeling response to myocardial infarction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f18ebf825bbb4dbca6e73911d2a8ceaf

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f18ebf825bbb4dbca6e73911d2a8ceaf

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI162188

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