Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cel...
Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo
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Author / Creator
Pennington, Britney O. , Bailey, Jeffrey K. , Faynus, Mohamed A. , Hinman, Cassidy , Hee, Mitchell N. , Ritts, Rory , Nadar, Vignesh , Zhu, Danhong , Mitra, Debbie , Martinez-Camarillo, Juan Carlos , Lin, Tai-Chi , Thomas, Biju B. , Hinton, David R. , Humayun, Mark S. , Lebkowski, Jane , Johnson, Lincoln V. and Clegg, Dennis O.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Age-related macular degeneration (AMD) is the primary cause of blindness in adults over 60 years of age, and clinical trials are currently assessing the therapeutic potential of retinal pigmented epithelial (RPE) cell monolayers on implantable scaffolds to treat this disease. However, challenges related to the culture, long-term storage, and long-d...
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Full title
Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo
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TN_cdi_doaj_primary_oai_doaj_org_article_f19a0c25861141a083ed1e359e044d22
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f19a0c25861141a083ed1e359e044d22
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-85631-6
