Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen h...
Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients
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Author / Creator
Páez-Franco, José C. , Torres-Ruiz, Jiram , Sosa-Hernández, Víctor A. , Cervantes-Díaz, Rodrigo , Romero-Ramírez, Sandra , Pérez-Fragoso, Alfredo , Meza-Sánchez, David E. , Germán-Acacio, Juan Manuel , Maravillas-Montero, José L. , Mejía-Domínguez, Nancy R. , Ponce-de-León, Alfredo , Ulloa-Aguirre, Alfredo , Gómez-Martín, Diana and Llorente, Luis
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
We identified the main changes in serum metabolites associated with severe (n = 46) and mild (n = 19) COVID-19 patients by gas chromatography coupled to mass spectrometry. The modified metabolic profiles were associated to an altered amino acid catabolism in hypoxic conditions. Noteworthy, three α-hydroxyl acids of amino acid origin increased with...
Alternative Titles
Full title
Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients
Authors, Artists and Contributors
Author / Creator
Torres-Ruiz, Jiram
Sosa-Hernández, Víctor A.
Cervantes-Díaz, Rodrigo
Romero-Ramírez, Sandra
Pérez-Fragoso, Alfredo
Meza-Sánchez, David E.
Germán-Acacio, Juan Manuel
Maravillas-Montero, José L.
Mejía-Domínguez, Nancy R.
Ponce-de-León, Alfredo
Ulloa-Aguirre, Alfredo
Gómez-Martín, Diana
Llorente, Luis
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f2049ab772c343f592bbd0ee9b7ddc09
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2049ab772c343f592bbd0ee9b7ddc09
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-85788-0