In Silico Mapping of Essential Residues in the Catalytic Domain of PDE5 Responsible for Stabilizatio...
In Silico Mapping of Essential Residues in the Catalytic Domain of PDE5 Responsible for Stabilization of Its Commercial Inhibitors
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Basel: MDPI AG
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English
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Basel: MDPI AG
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Phosphodiesterase type 5 (PDE5) is an important enzyme associated with the hydrolysis of cyclic guanosine monophosphate (cGMP) to guanosine monophosphate (GMP). Due to the relevant role of second messenger cGMP as a mediator in many physiological processes, efforts have been converged to find a safe pharmacological approach, seeking a specific, sel...
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In Silico Mapping of Essential Residues in the Catalytic Domain of PDE5 Responsible for Stabilization of Its Commercial Inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_f22782bbdc0b4e28aabf4f515d29868a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f22782bbdc0b4e28aabf4f515d29868a
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ISSN
2218-0532,0036-8709
E-ISSN
2218-0532
DOI
10.3390/scipharm87040029
