Haploidy in somatic cells is induced by mature oocytes in mice
Haploidy in somatic cells is induced by mature oocytes in mice
About this item
Full title
Author / Creator
Lee, Yeonmi , Trout, Aysha , Marti-Gutierrez, Nuria , Kang, Seoon , Xie, Philip , Mikhalchenko, Aleksei , Kim, Bitnara , Choi, Jiwan , So, Seongjun , Han, Jongsuk , Xu, Jing , Koski, Amy , Ma, Hong , Yoon, Junchul David , Van Dyken, Crystal , Darby, Hayley , Liang, Dan , Li, Ying , Tippner-Hedges, Rebecca , Xu, Fuhua , Amato, Paula , Palermo, Gianpiero D. , Mitalipov, Shoukhrat and Kang, Eunju
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Haploidy is naturally observed in gametes; however, attempts of experimentally inducing haploidy in somatic cells have not been successful. Here, we demonstrate that the replacement of meiotic spindles in mature metaphases II (MII) arrested oocytes with nuclei of somatic cells in the G0/G1 stage of cell cycle results in the formation of
de novo<...
Alternative Titles
Full title
Haploidy in somatic cells is induced by mature oocytes in mice
Authors, Artists and Contributors
Author / Creator
Trout, Aysha
Marti-Gutierrez, Nuria
Kang, Seoon
Xie, Philip
Mikhalchenko, Aleksei
Kim, Bitnara
Choi, Jiwan
So, Seongjun
Han, Jongsuk
Xu, Jing
Koski, Amy
Ma, Hong
Yoon, Junchul David
Van Dyken, Crystal
Darby, Hayley
Liang, Dan
Li, Ying
Tippner-Hedges, Rebecca
Xu, Fuhua
Amato, Paula
Palermo, Gianpiero D.
Mitalipov, Shoukhrat
Kang, Eunju
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f243e9eafa5043c39036acc809225b6e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f243e9eafa5043c39036acc809225b6e
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-03040-5
