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Preclinical Development of a Genetically Engineered Albumin‐Binding Nanoparticle of Paclitaxel

Preclinical Development of a Genetically Engineered Albumin‐Binding Nanoparticle of Paclitaxel

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f24ec2aa4c224b659763f6bcc87b8c31

Preclinical Development of a Genetically Engineered Albumin‐Binding Nanoparticle of Paclitaxel

About this item

Full title

Preclinical Development of a Genetically Engineered Albumin‐Binding Nanoparticle of Paclitaxel

Publisher

Germany: John Wiley & Sons, Inc

Journal title

Small science, 2024-11, Vol.4 (11), p.2400153-n/a

Language

English

Formats

Publication information

Publisher

Germany: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Nab‐paclitaxel (Abraxane), an albumin‐bound solvent‐free paclitaxel (PTX) formulation that takes advantage of the endogenous albumin transport pathway, is the current gold standard for treatment of solid tumors with PTX. However, nab‐paclitaxel has several limitations, including complex manufacturing, immunogenicity, slow drug‐release, and a narrow...

Alternative Titles

Full title

Preclinical Development of a Genetically Engineered Albumin‐Binding Nanoparticle of Paclitaxel

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f24ec2aa4c224b659763f6bcc87b8c31

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f24ec2aa4c224b659763f6bcc87b8c31

Other Identifiers

ISSN

2688-4046

E-ISSN

2688-4046

DOI

10.1002/smsc.202400153

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