Preclinical Development of a Genetically Engineered Albumin‐Binding Nanoparticle of Paclitaxel
Preclinical Development of a Genetically Engineered Albumin‐Binding Nanoparticle of Paclitaxel
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Germany: John Wiley & Sons, Inc
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English
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Germany: John Wiley & Sons, Inc
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Nab‐paclitaxel (Abraxane), an albumin‐bound solvent‐free paclitaxel (PTX) formulation that takes advantage of the endogenous albumin transport pathway, is the current gold standard for treatment of solid tumors with PTX. However, nab‐paclitaxel has several limitations, including complex manufacturing, immunogenicity, slow drug‐release, and a narrow...
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Preclinical Development of a Genetically Engineered Albumin‐Binding Nanoparticle of Paclitaxel
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TN_cdi_doaj_primary_oai_doaj_org_article_f24ec2aa4c224b659763f6bcc87b8c31
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f24ec2aa4c224b659763f6bcc87b8c31
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ISSN
2688-4046
E-ISSN
2688-4046
DOI
10.1002/smsc.202400153