Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA
Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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While genome recoding using quadruplet codons to incorporate non-proteinogenic amino acids is attractive for biotechnology and bioengineering purposes, the mechanism through which such codons are translated is poorly understood. Here we investigate translation of quadruplet codons by a +1-frameshifting tRNA,
SufB2
, that contains an extra nuc...
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Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA
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TN_cdi_doaj_primary_oai_doaj_org_article_f25e7830b887458f96ecdebbbd086160
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f25e7830b887458f96ecdebbbd086160
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20373-z