The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteome...
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
About this item
Full title
Author / Creator
Davydova, Erna , Shimazu, Tadahiro , Schuhmacher, Maren Kirstin , Jakobsson, Magnus E. , Willemen, Hanneke L. D. M. , Liu, Tongri , Moen, Anders , Ho, Angela Y. Y. , Małecki, Jędrzej , Schroer, Lisa , Pinto, Rita , Suzuki, Takehiro , Grønsberg, Ida A. , Sohtome, Yoshihiro , Akakabe, Mai , Weirich, Sara , Kikuchi, Masaki , Olsen, Jesper V. , Dohmae, Naoshi , Umehara, Takashi , Sodeoka, Mikiko , Siino, Valentina , McDonough, Michael A. , Eijkelkamp, Niels , Schofield, Christopher J. , Jeltsch, Albert , Shinkai, Yoichi , Falnes, Pål Ø. , Övriga starka forskningsmiljöer , Other Strong Research Environments , LUCC: Lund University Cancer Centre , Lunds Tekniska Högskola , Departments at LTH , Lunds universitet , Faculty of Engineering, LTH , Profilområden och andra starka forskningsmiljöer , Lund University , Department of Immunotechnology , Profile areas and other strong research environments , Institutioner vid LTH , Institutionen för immunteknologi and LUCC: Lunds universitets cancercentrum
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Post-translational methylation plays a crucial role in regulating and optimizing protein function. Protein histidine methylation, occurring as the two isomers 1- and 3-methylhistidine (1MH and 3MH), was first reported five decades ago, but remains largely unexplored. Here we report that METTL9 is a broad-specificity methyltransferase that mediates...
Alternative Titles
Full title
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Authors, Artists and Contributors
Author / Creator
Shimazu, Tadahiro
Schuhmacher, Maren Kirstin
Jakobsson, Magnus E.
Willemen, Hanneke L. D. M.
Liu, Tongri
Moen, Anders
Ho, Angela Y. Y.
Małecki, Jędrzej
Schroer, Lisa
Pinto, Rita
Suzuki, Takehiro
Grønsberg, Ida A.
Sohtome, Yoshihiro
Akakabe, Mai
Weirich, Sara
Kikuchi, Masaki
Olsen, Jesper V.
Dohmae, Naoshi
Umehara, Takashi
Sodeoka, Mikiko
Siino, Valentina
McDonough, Michael A.
Eijkelkamp, Niels
Schofield, Christopher J.
Jeltsch, Albert
Shinkai, Yoichi
Falnes, Pål Ø.
Övriga starka forskningsmiljöer
Other Strong Research Environments
LUCC: Lund University Cancer Centre
Lunds Tekniska Högskola
Departments at LTH
Lunds universitet
Faculty of Engineering, LTH
Profilområden och andra starka forskningsmiljöer
Lund University
Department of Immunotechnology
Profile areas and other strong research environments
Institutioner vid LTH
Institutionen för immunteknologi
LUCC: Lunds universitets cancercentrum
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f285ea6c5c6e4717b078c180ed9b6cd5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f285ea6c5c6e4717b078c180ed9b6cd5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20670-7
How to access this item
ERROR: Invalid URL specified.
