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Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tum...

Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tum...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2991e7204054ebb993d048929222b82

Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tumors during chemoradiation therapy

About this item

Full title

Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tumors during chemoradiation therapy

Publisher

Public Library of Science (PLoS)

Journal title

PloS one, 2022-10, Vol.17 (10), p.e0274457

Language

English

Formats

Publication information

Publisher

Public Library of Science (PLoS)

More information

Scope and Contents

Contents

BackgroundClinically relevant genetic predictors of radiation response for cervical cancer are understudied due to the morbidity of repeat invasive biopsies required to obtain genetic material. Thus, we aimed to demonstrate the feasibility of a novel noninvasive cervical swab technique to (1) collect tumor DNA with adequate throughput to (2) perfor...

Alternative Titles

Full title

Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tumors during chemoradiation therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f2991e7204054ebb993d048929222b82

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2991e7204054ebb993d048929222b82

Other Identifiers

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0274457

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