Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins
Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins
About this item
Full title
Author / Creator
Rosen, Osnat , Ozeri, Eyal , Barnea, Ada , David, Alon and Zichel, Ran
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
Botulinum neurotoxins are bacterial proteins that cause botulism, a life-threatening disease. Therapy relies mostly on post-intoxication antibody treatment. The only accepted method to measure the potency of, and to approve, antitoxin preparations is the mouse lethality neutralization bioassay. However, this assay is time-consuming, labor-intensive...
Alternative Titles
Full title
Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f2a5183b64ba43d5be57ab70a409f56c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2a5183b64ba43d5be57ab70a409f56c
Other Identifiers
ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins8100276
