Limbic system synaptic dysfunctions associated with prion disease onset
Limbic system synaptic dysfunctions associated with prion disease onset
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Misfolding of normal prion protein (PrP
C
) to pathological isoforms (prions) causes prion diseases (PrDs) with clinical manifestations including cognitive decline and mood-related behavioral changes. Cognition and mood are linked to the neurophysiology of the limbic system. Little is known about how the disease affects the synaptic activity...
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Full title
Limbic system synaptic dysfunctions associated with prion disease onset
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TN_cdi_doaj_primary_oai_doaj_org_article_f2da27e3e6a140d58104eb7598f0cc45
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2da27e3e6a140d58104eb7598f0cc45
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-024-01905-w
