Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features...
Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer
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Author / Creator
Ma, Lichun , Heinrich, Sophia , Wang, Limin , Keggenhoff, Friederike L. , Khatib, Subreen , Forgues, Marshonna , Kelly, Michael , Hewitt, Stephen M. , Saif, Areeba , Hernandez, Jonathan M. , Mabry, Donna , Kloeckner, Roman , Greten, Tim F. , Chaisaingmongkol, Jittiporn , Ruchirawat, Mathuros , Marquardt, Jens U. and Wang, Xin Wei
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Intratumor heterogeneity may result from the evolution of tumor cells and their continuous interactions with the tumor microenvironment which collectively drives tumorigenesis. However, an appearance of cellular and molecular heterogeneity creates a challenge to define molecular features linked to tumor malignancy. Here we perform multiregional sin...
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Full title
Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_f2ebde2426ee4ec09a8cd16dac1ffe6f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f2ebde2426ee4ec09a8cd16dac1ffe6f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-35291-5
