Genome editing of oncogenes with ZFNs and TALENs: caveats in nuclease design
Genome editing of oncogenes with ZFNs and TALENs: caveats in nuclease design
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Gene knockout technologies involving programmable nucleases have been used to create knockouts in several applications. Gene editing using Zinc-finger nucleases (ZFNs), Transcription activator like effectors (TALEs) and CRISPR/Cas systems has been used to create changes in the genome in order to make it non-functional. In the present study, we have...
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Full title
Genome editing of oncogenes with ZFNs and TALENs: caveats in nuclease design
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TN_cdi_doaj_primary_oai_doaj_org_article_f338d2877e864156b060b7ac49949603
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f338d2877e864156b060b7ac49949603
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ISSN
1475-2867
E-ISSN
1475-2867
DOI
10.1186/s12935-018-0666-0
