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Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infec...

Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f38c402d2a6340749497b7d56e6094d6

Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist

About this item

Full title

Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist

Publisher

American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2023-05, Vol.133 (10)

Language

English

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Publication information

Publisher

American Society for Clinical Investigation

Subjects

Subjects and topics

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Scope and Contents

Contents

Background Lung infections are among the most consequential manifestations of cystic fibrosis (CF) and are associated with reduced lung function and shortened survival. Drugs called CF transmembrane conductance regulator (CFTR) modulators improve activity of dysfunctional CFTR channels, which is the physiological defect causing CF. However, it is u...

Alternative Titles

Full title

Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist

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Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f38c402d2a6340749497b7d56e6094d6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f38c402d2a6340749497b7d56e6094d6

Other Identifiers

E-ISSN

1558-8238

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