Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling
Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling
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Author / Creator
Giamundo, Giuliana , Intartaglia, Daniela , Del Prete, Eugenio , Polishchuk, Elena , Andreone, Fabrizio , Ognibene, Marzia , Buonocore, Sara , Hay Mele, Bruno , Salierno, Francesco Giuseppe , Monfregola, Jlenia , Antonini, Dario , Grumati, Paolo , Eva, Alessandra , De Cegli, Rossella and Conte, Ivan
Publisher
England: eLife Sciences Publications, Ltd
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English
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England: eLife Sciences Publications, Ltd
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Contents
Endosomes have emerged as major signaling hubs where different internalized ligand-receptor complexes are integrated and the outcome of signaling pathways are organized to regulate the strength and specificity of signal transduction events. Ezrin, a major membrane-actin linker that assembles and coordinates macromolecular signaling complexes at mem...
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Full title
Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling
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TN_cdi_doaj_primary_oai_doaj_org_article_f3abf68db9114b948bb90b9393de3e7d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3abf68db9114b948bb90b9393de3e7d
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.98523
