Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small...
Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule
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Author / Creator
Cao, Shi-Ying , Hu, Yao , Chen, Cheng , Yuan, Fang , Xu, Min , Li, Qi , Fang, Kai-Heng , Chen, Yaoyu and Liu, Yan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Human pluripotent stem cells (hPSCs) play important role in studying the function of human glutamatergic neurons and related disease pathogenesis. However, the current hPSC-derived cortical system produced a significant number of inhibitory GABAergic neurons that reduced the purity of excitatory neurons. In this study, we established a robust hPSC-...
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Full title
Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule
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TN_cdi_doaj_primary_oai_doaj_org_article_f3af8a0054d549e5bf87dcd461c40c7d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3af8a0054d549e5bf87dcd461c40c7d
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-03519-w
