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Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different...

Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3b98da63d58464db84a7f1377e8342a

Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma

About this item

Full title

Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma

Publisher

Basel: BioMed Central

Journal title

Journal of biomedical science, 2021-06, Vol.28 (1), p.1-47, Article 47

Language

English

Formats

Publication information

Publisher

Basel: BioMed Central

More information

Scope and Contents

Contents

Background Elevated transforming growth factor (TGF)-β2 in aqueous humor (AH) has been suggested to contribute to trabecular meshwork (TM) fibrosis and intraocular pressure (IOP) regulation in primary open-angle glaucoma (POAG), but TGF-β2 is downregulated in secondary open-angle glaucoma (SOAG). Because autotaxin (ATX) is upregulated in SOAG, we i...

Alternative Titles

Full title

Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f3b98da63d58464db84a7f1377e8342a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3b98da63d58464db84a7f1377e8342a

Other Identifiers

ISSN

1423-0127,1021-7770

E-ISSN

1423-0127

DOI

10.1186/s12929-021-00745-3

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