Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice
Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Acute kidney injury is associated with high mortality, especially in intensive care unit patients. The polyol pathway is a metabolic route able to convert glucose into fructose. Here we show the detrimental role of endogenous fructose production by the polyol pathway and its metabolism through fructokinase in the pathogenesis of ischaemic acute kid...
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Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_f3cdc5cee4a04d45865650ca82efee0f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3cdc5cee4a04d45865650ca82efee0f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14181
