RNA Polymerase II transcription independent of TBP in murine embryonic stem cells
RNA Polymerase II transcription independent of TBP in murine embryonic stem cells
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England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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Transcription by RNA Polymerase II (Pol II) is initiated by the hierarchical assembly of the pre-initiation complex onto promoter DNA. Decades of research have shown that the TATA-box binding protein (TBP) is essential for Pol II loading and initiation. Here, we report instead that acute depletion of TBP in mouse embryonic stem cells has no global...
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Full title
RNA Polymerase II transcription independent of TBP in murine embryonic stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_f3dbb978e91b4b0dbade89a695ea59df
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3dbb978e91b4b0dbade89a695ea59df
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.83810
