Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-ba...
Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-based actomyosin symmetry breaking
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Subcellular fine-tuning of the actomyosin cytoskeleton is a prerequisite for polarized cell migration. We identify LSP (lymphocyte-specific protein) 1 as a critical regulator of actomyosin contractility in primary macrophages. LSP1 regulates adhesion and migration, including the parameters cell area and speed, and also podosome turnover, oscillatio...
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Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-based actomyosin symmetry breaking
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TN_cdi_doaj_primary_oai_doaj_org_article_f3f5c58257864c0498c0aecf08fa9c52
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3f5c58257864c0498c0aecf08fa9c52
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-02904-x
