Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone los...
Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Receptor activator of NFkB ligand (RANKL) is a TNF-family cytokine required for osteoclast formation, as well as immune cell and mammary gland development. It is produced as a membrane-bound protein that can be shed to form a soluble protein. We created mice harboring a sheddase-resistant form of RANKL, in which soluble RANKL is undetectable in the...
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Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss
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TN_cdi_doaj_primary_oai_doaj_org_article_f3fdb2bc80d5499aa847b891e2ea7b50
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f3fdb2bc80d5499aa847b891e2ea7b50
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05244-y
