rs2076295 variants influence nintedanib and pirfenidone outcomes in idiopathic pulmonary fibrosis: a...
rs2076295 variants influence nintedanib and pirfenidone outcomes in idiopathic pulmonary fibrosis: a pilot study
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Author / Creator
Martina Doubkova , Eva Kriegova , Simona Littnerova , Petra Schneiderova , Martina Sterclova , Vladimir Bartos , Martina Plackova , Monika Zurkova , Radka Bittenglova , Vladimira Lostaková , Lenka Siskova , Pavlina Lisa , Hana Suldova , Michael Doubek , Jana Psikalova , Tomas Snizek , Pavlina Musilova and Martina Vasakova
Publisher
SAGE Publishing
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English
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SAGE Publishing
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Background: The antifibrotic drugs nintedanib and pirfenidone are used for the treatment of idiopathic pulmonary fibrosis (IPF). We analysed the association of common profibrotic polymorphisms in MUC5B (mucin 5B, rs35705950) and DSP (desmoplakin, rs2076295) on antifibrotic treatment outcomes in IPF. Methods: MUC5B rs35705950 and DSP rs2076295 were...
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rs2076295 variants influence nintedanib and pirfenidone outcomes in idiopathic pulmonary fibrosis: a pilot study
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TN_cdi_doaj_primary_oai_doaj_org_article_f44baceebf1c45358ab4de31e662b434
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f44baceebf1c45358ab4de31e662b434
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E-ISSN
1753-4666
DOI
10.1177/17534666211042529
