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The novel compound PICCS improves cell viability during cold storage and reduces pulmonary ischemia-...

The novel compound PICCS improves cell viability during cold storage and reduces pulmonary ischemia-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f48186fdf1814e45b996746f05f9a6f6

The novel compound PICCS improves cell viability during cold storage and reduces pulmonary ischemia-reperfusion injury in a rat model

About this item

Full title

The novel compound PICCS improves cell viability during cold storage and reduces pulmonary ischemia-reperfusion injury in a rat model

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2025-04, Vol.15 (1), p.15217-10, Article 15217

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A simple method to achieve better organ preservation is the addition of compounds to the preservation solution, which effectively inhibits cold injury. We aimed to develop novel compounds for better lung graft preservation using TY52156 as a seed compound, which reportedly inhibits cold injury of vascular endothelial cells and exerts organ-protecti...

Alternative Titles

Full title

The novel compound PICCS improves cell viability during cold storage and reduces pulmonary ischemia-reperfusion injury in a rat model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f48186fdf1814e45b996746f05f9a6f6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f48186fdf1814e45b996746f05f9a6f6

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-025-99851-7

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