Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreact...
Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Sodium channel inhibitor drugs decrease pathological hyperactivity in various diseases including pain syndromes, myotonia, arrhythmias, nerve injuries and epilepsies. Inhibiting pathological but not physiological activity, however, is a major challenge in drug development. Sodium channel inhibitors exert their effects by a dual action: they obstruc...
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Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog
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TN_cdi_doaj_primary_oai_doaj_org_article_f48d2435c9aa4403b15cfc5aca00707f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f48d2435c9aa4403b15cfc5aca00707f
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-26444-y
