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Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy

Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f4deaa2647f04374a74ffe95884de6d6

Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy

About this item

Full title

Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy

Publisher

Cambridge: eLife Science Publications, Ltd

Journal title

eLife, 2021-07, Vol.10

Language

English

Formats

Publication information

Publisher

Cambridge: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Keratin intermediate filaments are an essential and major component of the cytoskeleton in epithelial cells. They form a stable yet dynamic filamentous network extending from the nucleus to the cell periphery, which provides resistance to mechanical stresses. Mutations in keratin genes are related to a variety of epithelial tissue diseases. Despite...

Alternative Titles

Full title

Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f4deaa2647f04374a74ffe95884de6d6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f4deaa2647f04374a74ffe95884de6d6

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.70307

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